Webb1 mars 2012 · Abstract. Hepatocellular carcinoma (HCC) is one of the most common visceral malignancies worldwide, with a very high incidence and poor prognosis. Bone morphogenesis protein 4 (BMP4), which belongs to the TGF-β superfamily of proteins, is a multifunctional cytokine, which exerts its biologic effects through SMAD- and non-SMAD … Webb1 juli 2013 · Because Smad4 is a central signaling molecule of TGF-β–induced signal transduction, we hypothesized that nestin expression status might depend on TGF-β1/Smad4 signaling. Nestin promoted tumor cell migration and induced EMT in PDAC We investigated whether nestin played a direct functional role in facilitating PDAC cell …
Anti-Smad4 Antibody (B-8) SCBT - Santa Cruz Biotechnology
WebbSAN TA C RUZ BI OTEC HNOL OG Y, INC . Smad4 (N-16): sc-1908 SantaCruzBiotechnology,Inc. 1.800.457.3801 831.457.3800 fax 831.457.3801 Europe +00800 4573 8000 49 6221 4503 0 www.scbt.com BACKGROUND Smad proteins, the mammalian homologs of the Drosophila mothers against dpp (Mad) have been … Webb1 okt. 2024 · Smad4 has 12 lysine residues locating in the MH1 domain, one lysine residue in the linker domain, and seven lysine residues in its MH2 domain, respectively. We made … how to draw a vector in standard position
SMAD4 antibody Western, ELISA SAB4501814 DPC4 - Sigma-Aldrich
Webb24 aug. 2013 · incubations with anti-SMAD4 antibody (B-8, sc-7966, Santa Cruz, USA) at 1:200 dilutions. were carried out overnight at 4 °C. Then, the specimens were briefly washed in PBS (3×5. WebbSmad4 or LOH (loss of heterozygosity) at 18q21 may be associated with a more aggressive phenotype in gastric, esophageal and pancreatic cancers, and intrahepatic … Webband a mouse anti‑Smad4 antibody (1:100; sc‑7966; Santa Cruz Biotechnology, Santa Cruz, CA, USA) were used as a primary antibody. Following an overnight incubation with the … leatrice christie of great bend kansas