High steacs trial

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WebNov 21, 2024 · High-sensitivity cardiac troponin (hs-cTn) assays facilitate the ruling-out of myocardial infarction (MI) but identify a high number of patients with elevated troponin … WebOct 15, 2024 · This study is a prespecified secondary analysis of the High-STEACS (High-Sensitivity Troponin in the Evaluation of Patients With Suspected Acute Coronary Syndrome) trial, which evaluated the impact of incorporating hs-TnI in the evaluation of patients suspected of ACS on outcomes. A total of 48,282 consecutive patients (47% women) with ...

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WebThe High-STEACS trial makes use of several routine electronic health-care data sources that are linked, de-identified, and held in DataLoch Safe Haven, which is accessible by approved individuals who have undertaken the necessary governance training. Summary aggregate level data and analysis code for this study can be made available upon ... WebNov 7, 2024 · The High-STEACS trial represents a challenge to the research field and fundamentally questions the current approach to the diagnosis of myocardial infarction. … pool builders hamilton nz

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WebJan 21, 2024 · The Universal Definition of Myocardial Infarction recommends high-sensitivity cardiac troponin testing and classification of patients with myocardial injury … WebHigh-STEACS pathway or the European Society of Cardiology 1-hour pathway. • A prospective randomized controlled trial evaluat-ing implementation of the High-STEACS pathway will provide further evidence of safety and efficacy in clinical practice and is due to report in early 2024. WebAug 1, 2024 · The High-STEACS trial (High-Sensitivity Troponin in the Evaluation of Patients With Suspected Acute Coronary Syndrome) 7 assessed whether implementing high-sensitivity cardiac troponin testing and the recommendations of the Universal Definition of Myocardial Infarction led to changes in investigation, treatment, and outcomes in patients … shaquille o\u0027neal how many rings

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Assessment of clinical effectiveness - High-sensitivity troponin …

WebNov 7, 2024 · Biological Science Troponin Diagnosing myocardial infarction in the era of high-sensitivity troponin: the High-STEACS trial Cardiovascular Research License CC BY 4.0 Authors: Atul Anand... WebJun 25, 2024 · High-STEACS is a stepped-wedge cluster randomized controlled trial that evaluated the implementation of a high-sensitivity cardiac troponin I assay in consecutive patients with suspected acute … shaquille o\u0027neal next to yao mingWebApr 17, 2024 · The High-STEACS trial was directly followed by the HiSTORIC trial, addressing similar research questions and using many of the same data sources. So we have been through the loop again which has made for a more streamlined process. pool builders inc norwood ma

"WebJul 11, 2024 · Trial Protocol and Statistical Analysis Plan Supplement 2. eMethods. eTable 1. Characteristics of the Study Population According to Adjudicated Diagnosis (Type 1 … " - High steacs trial

High steacs trial

WebAug 29, 2024 · When the STEACS Are High The study enrolled more than 48,000 consecutive patients presenting with chest pain to one of 10 Scottish hospitals, with all patients … WebHigh-STEACS Trial Protocol Version 7.0 16/05/2024 High-sensitivity Troponin in the Evaluation of patients with Acute Coronary Syndrome ( HighSTEACS): A randomised …

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WebAug 28, 2024 · The High-STEACS trial 5 is the first randomised trial to evaluate whether the introduction of a high-sensitivity cardiac troponin I assay with a 99th centile diagnostic threshold would reduce subsequent myocardial infarction or cardiovascular death at one year in patients with suspected acute coronary syndrome. WebJan 14, 2016 · The High-STEACS trial investigators conducted a prospective cohort study of 6,304 consecutively enrolled patients with suspected acute coronary syndrome presenting to four secondary and tertiary care hospitals in Scotland. They measured plasma troponin concentrations at presentation using a high-sensitivity cardiac troponin I assay.

WebThe aim of this trial was to find out whether heart attack survival rates could be improved by using a new high-sensitivity troponin test to make the diagnosis. What did the study … WebSep 4, 2024 · MUNICH — The first randomized controlled trial of the latest high-sensitivity cardiac troponin I assay in patients with suspected acute coronary syndrome showed the test increased detection of...

WebDec 10, 2024 · study of the High-STEACS trial (High-Sensitivity Troponin in the Evaluation of Patients With Acute Coronary Syndrome). All patients in whom the attending clinician requested car-diac troponin for suspected acute coronary syndrome were eligible for inclusion. We did not enroll patients with ST-segment–elevation myocardial infarction, … WebThe High-Sensitivity Troponin in the Evaluation of Patients With Acute Coronary Syndrome (High-STEACS) trial, 61 which contributed multiple diagnostic accuracy data sets, was a stepped-wedge cluster RCT that evaluated implementation of an early rule-out pathway in hospitals in Scotland.

WebDec 19, 2015 · This trial is registered with ClinicalTrials.gov (number NCT01852123). Findings: In patients without myocardial infarction at presentation, troponin concentrations were less than 5 ng/L in 2311 (61%) of 3799 patients, with a negative predictive value of 99·6% (95% CI 99·3-99·8) for the primary outcome.

WebOct 14, 2024 · The High-STEACS trial presented an opportunity to explore whether improved diagnostic testing—by transitioning from a conventional to a high-sensitivity cardiac troponin I test, using sex-specific thresholds, and applying the recommendations of the universal definition of MI—had differential impacts on the evaluation, treatment, and outcomes of … pool builders in beaumont texasWebMar 14, 2024 · When the outcome of a standardized test is used as the sole determining factor for making a major decision, it is known as high-stakes testing. Common examples … shaquille o\u0027neal next to normal thingsWebAug 28, 2024 · The High-STEACS trial 4 is the first randomised trial to evaluate whether the introduction of a high-sensitivity cardiac troponin I ... High-STEACS on Tuesday 28 August from 15:55 to 16:20 CEST on ... pool builders in broward countyWebAug 3, 2012 · Dr. Jolly, the lead investigator of RIVAL, noted that a key aspect of the RIFLE-STEACS trial is the experience level of the operators. “The message is that it’s likely you will see a benefit with radial access in STEMI with high-volume operators who are experienced with the radial technique,” he said. “I see this as quite encouraging ... pool builders in central texasWebApr 1, 2024 · This large multicenter trial of close to 31,500 patients from seven centers in Scotland confirms dramatic benefits of adopting an early rule-out strategy, with a 3.3-hour reduction in length of stay in the ED and a 59% decrease in hospital admission, without impacting safety. shaquille o\u0027neal next to his wifeWebNov 15, 2024 · The High-STEACS pathway identified 63.4% (1218/1920) of patients as low risk, with five missed events (four index type 1 myocardial infarction and one type 1 myocardial infarction at 30 days) for an NPV of 99.5% (95% CI 99.1% to 99.8%) and sensitivity of 98.0% (95% CI 96.4% to 99.5%). pool builders in alabamaWebSep 20, 2024 · The High-STEACS trial adopted a stepped-wedge, cluster-randomization of 10 hospitals in Scotland, and consisted of 2 phases: a validation phase of 6 months … pool builders in citrus county fl